DocumentCode :
3734833
Title :
A three-dimensional flow focusing microsecond mixer for dynamic assessment of nanoparticle formation
Author :
Liguo Jiang;Shuhuai Yao
Author_Institution :
HKUST Jockey Club Institute for Advanced Study, The Hong Kong University of Science and Technology, China
fYear :
2015
fDate :
7/1/2015 12:00:00 AM
Firstpage :
1159
Lastpage :
1162
Abstract :
This paper reports the design, fabrication, and characterization of a three-dimensional (3D) flow focusing microfluidic mixer. By hydrodynamically focusing the sample into a very confined stream in both vertical and horizontal directions, the mixer can achieve ultrarapid mixing of the sample stream with the reagent streams within ~3 ± 1 μs, which allows us to study the reaction kinetics on the microsecond timescale. Using the mixer, we investigated the formation of the hexaphenylsilole (HPS) nanoparticles. The HPS nanoparticles formed in the mixer have smaller size with narrower size distribution, compared to those formed by bulk nanoprecipitation. We also demonstrated the mixer can resolve the microsecond kinetics of nanoparticle self-assembly in two distinct steps, suggesting the nanoparticle formation follows the classical nucleation and growth theory.
Keywords :
"Mixers","Nanoparticles","Kinetic theory","Focusing","Three-dimensional displays","Self-assembly","Fluorescence"
Publisher :
ieee
Conference_Titel :
Nanotechnology (IEEE-NANO) , 2015 IEEE 15th International Conference on
Type :
conf
DOI :
10.1109/NANO.2015.7388831
Filename :
7388831
Link To Document :
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