• DocumentCode
    3734934
  • Title

    Aptasensor for diabetes mellitus detection and monitoring

  • Author

    Deanpen Japrung;Chayacon Apiwat;Kiatnida Treerattrakoon;Tararaj Dharakul;Patraporn Luksirikul

  • Author_Institution
    National Nanotechnology Center, National Science and Technology Development Agency, Thailand Science Park, Pathumthani, Thailand
  • fYear
    2015
  • fDate
    7/1/2015 12:00:00 AM
  • Firstpage
    1521
  • Lastpage
    1524
  • Abstract
    DNA aptamers against GHSA, which is protein marker for diabetes mellitus, were selected and modified. In combination properties of modified GHSA binding aptamer and fluorescence quenching of GO, we develop simple and sensitive platform for detection of GHSA in both PBS and human serum with the LOD of 50 μg/mL. We envision that our GO-aptamer platform has a potential to be GHSA detection for screening and monitoring diabetes mellitus.
  • Keywords
    "Fluorescence","DNA","Graphene","Proteins","Yttrium","Diabetes","Monitoring"
  • Publisher
    ieee
  • Conference_Titel
    Nanotechnology (IEEE-NANO) , 2015 IEEE 15th International Conference on
  • Type

    conf

  • DOI
    10.1109/NANO.2015.7388933
  • Filename
    7388933
    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=49&DC=3734934