Development of a triangular micro well for single cell trapping ? Computational study

The aim of this study is to find appropriate parameters of a trapping device, i.e. equilateral triangular microwell array, using a computational simulation. This simulation was divided into nine cases of microwell with various depths and widths to help analyze the effects of them on velocity and vorticity distribution induced inside the microwell. The microwells with equilateral length of 40, 60 and 80μm, and each length consisted of three depths, i.e. 15, 30 and 45 μm, were studied. The results suggested that the equilateral triangular 40-μm microwell with the depth of 30 μm should be able to effectively trap a 10-20 μm particle.