Osteoblast proliferation on graphene oxide eletrodeposited on anodized titanium

A bone-implant surface of anodized titanium (ATi) with graphene oxide (GO) composites showed the potentials of biocompatibility and antibacterial property. The aim of this study was to fabricate anodized titanium, coated with graphene oxide (ATiGO) alone, using anodization and anodic electrophoretic deposition, respectively. Scanning electron microscopy (SEM) was performed to investigate surface topography. The physiochemical properties of samples were evaluated by energy-dispersive X-ray spectroscope (EDX) and X-ray diffractrometer (XRD). Cell proliferation of mouse osteoblastic cell line (MC3T3-E1) was investigated using MTT assay on ATiGO, GO coated on titanium (TiGO), ATi, and commercially pure titanium (Ti). The preliminary results in this study suggest that GO coatings promote osteoblast proliferation after 3 and 5 days of cultures when compared with ATi and pure Ti.