• DocumentCode
    3747143
  • Title

    Mathematical modeling of the role of cooperativity between contractile and regulatory proteins in the mechano-calcium feedbacks in myocardium

  • Author

    E Shikhaleva;T Sulman;A Dokuchaev;Larisa V Nikitina;Leonid B Katsnelson

  • Author_Institution
    Institute of Immunology and Physiology, Ural Branch of Russian Academy of Sciences, Ekaterinburg, Russia
  • fYear
    2015
  • Firstpage
    321
  • Lastpage
    324
  • Abstract
    There is a complicated interplay between different factors contributing to the calcium regulation of the heart muscle contraction. Mathematical modeling is an efficient approach to analyze this compound system and recognize the key links. In this work the modeling is applied to the analysis of mechano-calcium feedback mechanisms and their role in the cardiomyocyte calcium activation.
  • Keywords
    "Transient analysis","Myocardium","Load modeling","Analytical models","Computational modeling","Data models"
  • Publisher
    ieee
  • Conference_Titel
    Computing in Cardiology Conference (CinC), 2015
  • ISSN
    2325-8861
  • Print_ISBN
    978-1-5090-0685-4
  • Electronic_ISBN
    2325-887X
  • Type

    conf

  • DOI
    10.1109/CIC.2015.7408651
  • Filename
    7408651
    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=49&DC=3747143