An ultra thin implantable system for cerebral blood volume monitoring using flexible OLED and OPD

An ultra thin implantable system using flexible organic light emitting diodes (OLEDs) and organic photodetectors (OPDs) on parylene substrate shows biocompatibility and high conformability on any surface. This system was used to monitor variations in cerebral blood volume (CBV) corresponding to an epileptic seizure, along with baseline signals such as heartbeat, respiration and slow sinusoidal hemodynamic oscillations (SSHOs). As such, this system shows strong potential for implantable and/or wearable biosensors for continuous health monitoring.