DocumentCode :
3763105
Title :
Highly dynamic self-organizing SMG morphogenesis in 3D culture
Author :
Mahmoud Farahat;Gulsan Ara Sathi;Hiroaki Taketa;Masamitsu Oshima;Takuo Kuboki;Takuya Matsumoto
Author_Institution :
Department of Biomaterials, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences. 2-5-1 Shikata-cho, 700-8558, Japan
fYear :
2015
Firstpage :
1
Lastpage :
3
Abstract :
Biological tissues have specific cell patterns and well-organized structures which result from various organogenesis processes. Among which is branching morphogenesis which is the key developmental processes for many glandular tissues including lungs, kidney, salivary gland and liver. Many approaches were suggested to regenerate salivary gland tissue in vitro. Here, we developed a 3D culture technique to study and recapitulate the dynamic forces generated during SMG organogenesis by utilizing time lapse live imaging to monitor the cellular migration and reorganization process of both epithelium and mesenchyme cells.
Keywords :
"Aggregates","Monitoring","Biomedical monitoring","Software","Lead","Salivary glands"
Publisher :
ieee
Conference_Titel :
Micro-NanoMechatronics and Human Science (MHS), 2015 International Symposium on
Type :
conf
DOI :
10.1109/MHS.2015.7438259
Filename :
7438259
Link To Document :
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