Prediction of spontaneous behavioral dynamics by neuronal population imaging in mouse neocortex

How does an animal in a steady environment self-initiate various behaviors? Results in this study suggest that the complex dynamic of spontaneous behavior in mice was highly deterministic. By temporally correlating three basic neuronal network properties, we can predict many minutes of spontaneous behavior. This description and prediction of neuronal activity and behavior may refine our knowledge about information processing in the brain and its linkage to animal behavior.