Title :
Integrated potentiostat for neurotransmitter sensing
Author :
K. Murari;M. Stanacevic;G. Cauwenberghs;N.V. Thakor
Author_Institution :
Sch. of Medicine, Johns Hopkins Univ., Baltimore, MD, USA
Abstract :
We have presented a chemical analysis paradigm for neurochemical studies, as opposed to the traditional electrophysiological regime. We described electrochemical analysis and the instrumentation involved in doing such analysis. The article presents the design and characterization of a 16-channel, high-sensitivity, wide-range VLSI potentiostat. We demonstrate the use of this potentiostat in real-time in vitro monitoring of the neurotransmitter dopamine.
Keywords :
"Neurotransmitters","Very large scale integration","Neurons","Nervous system","Chemicals","Electrodes","Current measurement","CMOS technology","Positron emission tomography","Sensor phenomena and characterization"
Journal_Title :
IEEE Engineering in Medicine and Biology Magazine
DOI :
10.1109/MEMB.2005.1549726
