Analysis of HIV proteins using DSP techniques

Author

Cosic, Irena

Author_Institution

Dept. of Electr. & Comput. Syst. Eng., Monash Univ., Clayton, Vic., Australia

Volume

3

fYear

2001

fDate

2001

Firstpage

2886

Abstract

Our previous studies suggested that digital signal processing methods can be used to analyse linear sequences of amino acids to reveal the functional informational within the protein sequence. In this study both spectral and time-frequency methods are applied to the analysis of the functional content of HIV virus envelope proteins. Here, we have identified specific RRM frequency of HIV proteins, predicted active sites in these proteins and compared these predictions with experimentally determined active sites.

Keywords

biochemistry; medical signal processing; molecular biophysics; proteins; spectral analysis; time-frequency analysis; CD4 molecule; HIV proteins analysis; HIV virus envelope proteins; acquired immunodeficiency syndrome; amino acids sequences; cell depletion; digital signal processing methods; experimentally determined active sites; functional informational; host cells infection; human immunodeficiency virus; predicted active sites; Amino acids; Continuous wavelet transforms; Digital signal processing; Frequency; Human immunodeficiency virus; Peptides; Proteins; Resonance; Sequences; Wavelet transforms;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 2001. Proceedings of the 23rd Annual International Conference of the IEEE

ISSN

1094-687X

Print_ISBN

0-7803-7211-5

Type

conf

DOI

10.1109/IEMBS.2001.1017392

Filename

1017392