Title :
Spatiotemporal dynamics of pacing in models of anatomical reentry
Author :
Sinha, Sitabhra ; Christini, David J.
Author_Institution :
Div. of Cardiology, Cornell Univ., New York, NY, USA
Abstract :
Reentry around non-conducting ventricular scar tissue, which often causes lethal arrhythmias, is typically treated by rapid stimulation from an implantable defibrillator. However, the mechanisms of termination (success and failure) are poorly understood. To elucidate such mechanisms, we studied pacing of anatomical reentry in 1-D and 2-D excitable cardiac media models. Our results suggest that the existence of inhomogeneity in the reentry circuit is essential for pacing termination of tachycardia to be successful. Considering the role of such inhomogeneities may lead to more effective pacing algorithms
Keywords :
biocontrol; bioelectric phenomena; cardiology; defibrillators; neurophysiology; physiological models; 1-D excitable cardiac media models; 2-D excitable cardiac media models; anatomical reentry models; cardiac tissue; failure; implantable defibrillator; inhomogeneity; lethal arrhythmias; more effective pacing algorithms; nonconducting ventricular scar tissue; pacing spatiotemporal dynamics; rapid stimulation; reentry circuit; success; tachycardia; termination mechanisms; Acceleration; Biophysics; Cardiology; Circuits; Educational institutions; Fibrillation; Medical treatment; Physics; Physiology; Spatiotemporal phenomena;
Conference_Titel :
Engineering in Medicine and Biology Society, 2001. Proceedings of the 23rd Annual International Conference of the IEEE
Conference_Location :
Istanbul
Print_ISBN :
0-7803-7211-5
DOI :
10.1109/IEMBS.2001.1018847
