DocumentCode :
380556
Title :
Bursting of neurons under slow wave stimulation
Author :
Zhu, Jun-Ling ; Shen, Qiang ; Jiang, Da-Zong
Author_Institution :
Inst. of Biomed. Eng., Xi´´an Jiaotong Univ., China
Volume :
1
fYear :
2001
fDate :
2001
Firstpage :
814
Abstract :
Hopf bifurcation of the H-H neuron was computed by numerical methods and discharge of H-H neuron under slow wave stimulation was studied by simulation. It is shown that slow wave can result in neuron bursting, especially the long time-course bursting, and onset of the bursting is related with Hopf bifurcation. The results prompt that bursting and supernormal excitability of neurons can be induced by slow excitatory synaptic reaction when it is big enough. This phenomenon probably can be used to explain the seizure of some diseases (such as epilepsy).
Keywords :
bioelectric potentials; cellular biophysics; neurophysiology; physiological models; H-H neuron; Hodgkin-Huxley neuron; Hopf bifurcation; epilepsy; neurons bursting; numerical methods; seizure; slow excitatory synaptic reaction; slow wave stimulation; supernormal excitability; Bifurcation; Biomedical computing; Biomedical engineering; Biomembranes; Computational modeling; Diseases; Epilepsy; Frequency; Mathematical model; Neurons;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Engineering in Medicine and Biology Society, 2001. Proceedings of the 23rd Annual International Conference of the IEEE
ISSN :
1094-687X
Print_ISBN :
0-7803-7211-5
Type :
conf
DOI :
10.1109/IEMBS.2001.1019065
Filename :
1019065
Link To Document :
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