Acoustic plate mode tissue sensor

Author

Tseng, F.G. ; Leou, K.C. ; Pan, L.C. ; Lai, Y.Y. ; Liang, Y.C. ; Hen, L. D C

Author_Institution

Eng. & Syst. Sci. Dept, Nat. Tsing Hua Univ., Hsinchu, Taiwan

Volume

1

fYear

2002

fDate

2002

Firstpage

278

Abstract

This paper reports a novel application of acoustic plate mode (APM) sensor to monitor processes of tissue regeneration. The sensor was tested at four different environments, including air, alcohol, DI water, and glycerol. Calibration of the sensor under solution with different densities has also been carried out, and demonstrated a density sensitivity of 29.36 degree/g/cm³. In the application as a tissue sensor, C3H10T1/2 fibroblast cell lines from a mouse embryo were incubated on the surface of the electrode-less sensor side. Initial test results showed a promising biocompatibility and feasibility of utilizing an APM sensor for quantitatively cell status analysis in the vitro condition.

Keywords

acoustic transducers; biological tissues; biosensors; calibration; cellular biophysics; condition monitoring; patient monitoring; quartz; sensitivity; C3H10T1/2 fibroblast cell lines; SiO₂; acoustic plate mode tissue sensor; biocompatibility; biosensor; calibration; cell status analysis; cultured cell proliferation processes; density sensitivity; monitoring; mouse embryo; quartz based sensor; tissue regeneration; Acoustic applications; Acoustic sensors; Acoustic testing; Biosensors; Calibration; Embryo; Fibroblasts; Mice; Monitoring; Underwater acoustics;

fLanguage

English

Publisher

ieee

Conference_Titel

Sensors, 2002. Proceedings of IEEE

Print_ISBN

0-7803-7454-1

Type

conf

DOI

10.1109/ICSENS.2002.1037099

Filename

1037099