Title :
3-D maximum likelihood reconstructions of viruses from cryo electron microscope images and parallel computation
Author :
Zheng, Yili ; Yin, Zhye ; Doerschuk, Peter C.
Author_Institution :
Sch. of Electr. & Comput. Eng., Purdue Univ., West Lafayette, IN, USA
Abstract :
A statistical method for computing 3-D reconstructions of virus particles from cryo electron microscope images and minimal prior information - particle symmetry and radii - is described. Two different approaches for parallel implementation of the algorithm are described based on parallel processing of different images and based on parallel numerical integration and numerical results showing nearly linear speedup are presented.
Keywords :
biology computing; electron microscopy; image reconstruction; integration; microorganisms; parallel algorithms; statistical analysis; 3D maximum likelihood reconstruction; cryo electron microscope images; parallel algorithm; parallel computation; parallel image processing; parallel numerical integration; particle radii; particle symmetry; signal reconstruction; statistical method; virus particles; Concurrent computing; Electron beams; Electron microscopy; Fourier transforms; Image reconstruction; Parallel processing; Particle scattering; Statistical analysis; Three dimensional displays; Viruses (medical);
Conference_Titel :
Image Processing. 2002. Proceedings. 2002 International Conference on
Print_ISBN :
0-7803-7622-6
DOI :
10.1109/ICIP.2002.1040026