DocumentCode
384335
Title
Extracting fractal features for analyzing protein structure
Author
Tao, Yu ; Ioerger, Thomas R. ; Sacchettini, James C.
Author_Institution
Shenzhen Graduate Sch., Tsinghua Univ., Beijing, China
Volume
2
fYear
2002
fDate
2002
Firstpage
482
Abstract
This paper is concerned with the development of a computational methodology based on fractal geometry for determining 3D structure of protein with imagery projection operations. In this investigation, the density-map image is a 2D projection of the 3D electron density map according to its depth of the density distribution along the projection direction. We extract fractal features of the density-map image in a region and use these features to look for candidate regions with similar patterns of density-map. We analyze its fractal signatures for determining 3D pattern of regions of density distribution. This paper presents preliminary results of such a study, wherein the protein surface was assumed to be a fractal, and computed fractal features (fractal dimension and fractal signature) were analyzed and found to possess fairly reasonable pattern for improving the discrimination abilities of the protein structure.
Keywords
computational geometry; feature extraction; 3D electron density map; candidate regions; computational methodology; density-map image; fractal features extraction; fractal geometry; imagery projection operations; Biology computing; Computer science; Electrons; Feature extraction; Fractals; Pattern analysis; Pattern recognition; Proteins; Rough surfaces; Surface roughness;
fLanguage
English
Publisher
ieee
Conference_Titel
Pattern Recognition, 2002. Proceedings. 16th International Conference on
ISSN
1051-4651
Print_ISBN
0-7695-1695-X
Type
conf
DOI
10.1109/ICPR.2002.1048343
Filename
1048343
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