• DocumentCode
    384335
  • Title

    Extracting fractal features for analyzing protein structure

  • Author

    Tao, Yu ; Ioerger, Thomas R. ; Sacchettini, James C.

  • Author_Institution
    Shenzhen Graduate Sch., Tsinghua Univ., Beijing, China
  • Volume
    2
  • fYear
    2002
  • fDate
    2002
  • Firstpage
    482
  • Abstract
    This paper is concerned with the development of a computational methodology based on fractal geometry for determining 3D structure of protein with imagery projection operations. In this investigation, the density-map image is a 2D projection of the 3D electron density map according to its depth of the density distribution along the projection direction. We extract fractal features of the density-map image in a region and use these features to look for candidate regions with similar patterns of density-map. We analyze its fractal signatures for determining 3D pattern of regions of density distribution. This paper presents preliminary results of such a study, wherein the protein surface was assumed to be a fractal, and computed fractal features (fractal dimension and fractal signature) were analyzed and found to possess fairly reasonable pattern for improving the discrimination abilities of the protein structure.
  • Keywords
    computational geometry; feature extraction; 3D electron density map; candidate regions; computational methodology; density-map image; fractal features extraction; fractal geometry; imagery projection operations; Biology computing; Computer science; Electrons; Feature extraction; Fractals; Pattern analysis; Pattern recognition; Proteins; Rough surfaces; Surface roughness;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Pattern Recognition, 2002. Proceedings. 16th International Conference on
  • ISSN
    1051-4651
  • Print_ISBN
    0-7695-1695-X
  • Type

    conf

  • DOI
    10.1109/ICPR.2002.1048343
  • Filename
    1048343