Title :
A microfluid test-bed with nanopore membranes for in-vitro simulation of flow characteristics of glaucoma drainage devices
Author :
Pan, Tingrui ; Brown, J. David ; Ziaie, Babak
Author_Institution :
Dept. of Electr. & Comput. Eng., Minnesota Univ., USA
Abstract :
In this paper, we report on a microfluidic test-bed for in-vitro simulation of flow characteristics of valved-glaucoma drainage devices. A nanopore membrane is used to mimic the fibrous tissue encapsulation of the sub-conjunctival plate following surgery. Pressure measurements with and without the valve clearly demonstrated the persisting effect of the microvalve in regulating the intraocular pressure subsequent to the fibrous capsule formation.
Keywords :
diseases; eye; membranes; microfluidics; patient treatment; pressure control; pressure measurement; fibrous tissue encapsulation; flow characteristics; glaucoma drainage devices; in-vitro simulation; intraocular pressure regulation; microfluid test-bed; nanopore membranes; persisting effect; subconjunctival plate; valve; Biomembranes; Encapsulation; In vitro; Microfluidics; Microvalves; Nanoporous materials; Pressure measurement; Surgery; Testing; Valves;
Conference_Titel :
Engineering in Medicine and Biology, 2002. 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society EMBS/BMES Conference, 2002. Proceedings of the Second Joint
Print_ISBN :
0-7803-7612-9
DOI :
10.1109/IEMBS.2002.1053048
