Title :
Non-invasive multi-modality technique to study angiogenesis associated with Kaposi´s sarcoma
Author :
Hassan, Moinuddin ; Hattery, David ; Chernomordik, Viktor ; Aleman, Karen ; Wyvill, Kathleen ; Merced, Florentino ; Little, Richard ; Yarchoan, Robert ; Gandjbakhche, Amir H.
Author_Institution :
Nat. Inst. of Child Health & Human Dev., Nat. Inst. of Health, Bethesda, MD, USA
Abstract :
In this on going study, we are investigating the usefulness of thermography and laser Doppler imaging techniques to study vascularity and vascular changes associated with Kaposi´s sarcoma. Both techniques are useful for observing the lesions associated with Kaposi´s sarcoma. A comparative image analysis of thermography, between the lesion and the contralateral, lesion free sites, shows that lesions are a different temperature than the contralateral side. Similar relationships are also observed in laser Doppler images. The present data supports further study of these imaging modalities to assess Kaposi´s sarcoma.
Keywords :
Doppler measurement; biomedical optical imaging; biothermics; blood vessels; haemorheology; infrared imaging; laser applications in medicine; tumours; Kaposi sarcoma; angiogenesis; blood perfusion; comparative image analysis; contralateral lesion free sites; contralateral side; imaging modalities; laser Doppler imaging techniques; lesions; noninvasive multi-modality technique; skin temperature; thermography; vascular changes; vascularity; veins; Blood flow; Cancer; Humans; Laser transitions; Lesions; Optical imaging; Pediatrics; Skin; Temperature sensors; Wavelength measurement;
Conference_Titel :
Engineering in Medicine and Biology, 2002. 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society EMBS/BMES Conference, 2002. Proceedings of the Second Joint
Print_ISBN :
0-7803-7612-9
DOI :
10.1109/IEMBS.2002.1106315