Title :
"Pull Moves" for Rectangular Lattice Polymer Models Are Not Fully Reversible
Author :
Dániel Györffy;Péter Závodszky;András Szilágyi
Author_Institution :
Hungarian Academy of Sciences, Budapest
Abstract :
"Pull moves” is a popular move set for lattice polymer model simulations. We show that the proof given for its reversibility earlier is flawed, and some moves are irreversible, which leads to biases in the parameters estimated from the simulations. We show how to make the move set fully reversible.
Keywords :
"Mathematical model","Lattices","Computational biology","Bioinformatics","Polymers"
Journal_Title :
IEEE/ACM Transactions on Computational Biology and Bioinformatics
DOI :
10.1109/TCBB.2012.129