Atherosclerotic human carotid bifurcations: mechanical and histological factors

Author

Kaazempur-Mofrad, M. ; Isasi, A. ; Younis, H. ; Chan, R. ; Hinton, D. ; Sukhova, G. ; Kamm, R.

Volume

2

fYear

2002

fDate

2002

Firstpage

1256

Abstract

3D finite element analyses were conducted of the diseased carotid bifurcation using reconstructed models based on in vivo MRI geometries and ultrasound velocity measurements. The resulting wall shear stress (WSS) and oscillatory shear index (OSI) distributions were correlated to histological parameters involved in atherogenesis.

Keywords

biomechanics; biomedical MRI; biomedical ultrasonics; blood vessels; diseases; finite element analysis; physiological models; ultrasonic velocity measurement; 3D finite element analyses; atherogenesis; atherosclerotic human carotid bifurcations; diseased carotid bifurcation; histological factors; histological parameters; in vivo MRI geometries; mechanical factors; medical diagnostic imaging; oscillatory shear index distributions; ultrasound velocity measurements; wall shear stress; Bifurcation; Finite element methods; Geometry; Humans; In vivo; Magnetic resonance imaging; Solid modeling; Stress; Ultrasonic imaging; Velocity measurement;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology, 2002. 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society EMBS/BMES Conference, 2002. Proceedings of the Second Joint

ISSN

1094-687X

Print_ISBN

0-7803-7612-9

Type

conf

DOI

10.1109/IEMBS.2002.1106375

Filename

1106375