A method for rapid simulation of propagating wave fronts in three-dimensional cardiac muscle with spatially-varying fiber orientations

Author

Feldman, A.B. ; Murphy, S.P. ; Coolahan, J.E.

Author_Institution

Appl. Phys. Lab., Johns Hopkins Univ., Laurel, MD, USA

Volume

2

fYear

2002

fDate

2002

Firstpage

1419

Abstract

We describe a simple cellular automata model for cardiac electrical activation that can simulate propagation in 3D muscle with arbitrary local fiber orientations. The model is computationally efficient and can provide activation sequences for rapidly driving models of cardiac mechanics. Here we show how to compute the model parameters from tissue parameters and successfully demonstrate rapid simulation of wave fronts in a slab of tissue with a rotating fiber structure.

Keywords

bioelectric potentials; biological tissues; biomechanics; cardiovascular system; cellular automata; muscle; physiological models; 3D muscle; activation sequences; cardiac electrical activation; cardiac mechanics; cardiovascular system; computationally efficient model; local fiber orientations; model parameters; propagating wave fronts; rapid simulation; rotating fiber structure tissue slab; simple cellular automata model; spatially-varying fiber orientations; three-dimensional cardiac muscle; tissue parameters; Cardiovascular system; Computational modeling; Heart; Integrated circuit modeling; Laboratories; Muscles; Physics; Slabs; Switches; Thyristors;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology, 2002. 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society EMBS/BMES Conference, 2002. Proceedings of the Second Joint

ISSN

1094-687X

Print_ISBN

0-7803-7612-9

Type

conf

DOI

10.1109/IEMBS.2002.1106459

Filename

1106459