Title :
A method for rapid simulation of propagating wave fronts in three-dimensional cardiac muscle with spatially-varying fiber orientations
Author :
Feldman, A.B. ; Murphy, S.P. ; Coolahan, J.E.
Author_Institution :
Appl. Phys. Lab., Johns Hopkins Univ., Laurel, MD, USA
Abstract :
We describe a simple cellular automata model for cardiac electrical activation that can simulate propagation in 3D muscle with arbitrary local fiber orientations. The model is computationally efficient and can provide activation sequences for rapidly driving models of cardiac mechanics. Here we show how to compute the model parameters from tissue parameters and successfully demonstrate rapid simulation of wave fronts in a slab of tissue with a rotating fiber structure.
Keywords :
bioelectric potentials; biological tissues; biomechanics; cardiovascular system; cellular automata; muscle; physiological models; 3D muscle; activation sequences; cardiac electrical activation; cardiac mechanics; cardiovascular system; computationally efficient model; local fiber orientations; model parameters; propagating wave fronts; rapid simulation; rotating fiber structure tissue slab; simple cellular automata model; spatially-varying fiber orientations; three-dimensional cardiac muscle; tissue parameters; Cardiovascular system; Computational modeling; Heart; Integrated circuit modeling; Laboratories; Muscles; Physics; Slabs; Switches; Thyristors;
Conference_Titel :
Engineering in Medicine and Biology, 2002. 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society EMBS/BMES Conference, 2002. Proceedings of the Second Joint
Print_ISBN :
0-7803-7612-9
DOI :
10.1109/IEMBS.2002.1106459
