Title :
Estimation of noise-corrected pulmonary blood flow heterogeneity using positron emission tomography
Author :
Winkler, T. ; Martinez, M. ; Layfield, D. ; Venegas, J.G.
Author_Institution :
Dept of Anesthesia & Biomed. Eng., Harvard Med. Sch., Boston, MA, USA
Abstract :
The coefficient of variation (CoV) is frequently used to describe functional or structural heterogeneity but is overestimated by the contribution of noise from the measurement method. We evaluated a method to estimate a noise-corrected heterogeneity. It delivers results with a narrow confidence interval. That method has been used to estimate the heterogeneity of pulmonary blood flow in humans as well as in animals.
Keywords :
blood flow measurement; image denoising; lung; medical image processing; positron emission tomography; animals; coefficient of variation; cylindrical phantom; functional heterogeneity; humans; measurement method; narrow confidence interval; noise-corrected pulmonary blood flow heterogeneity estimation; positron emission tomography; structural heterogeneity; Anesthesia; Biomedical measurements; Blood flow; Fluid flow measurement; Humans; Imaging phantoms; Linear regression; Noise measurement; Positron emission tomography; Signal to noise ratio;
Conference_Titel :
Engineering in Medicine and Biology, 2002. 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society EMBS/BMES Conference, 2002. Proceedings of the Second Joint
Print_ISBN :
0-7803-7612-9
DOI :
10.1109/IEMBS.2002.1106516
