Estimation of noise-corrected pulmonary blood flow heterogeneity using positron emission tomography

Author

Winkler, T. ; Martinez, M. ; Layfield, D. ; Venegas, J.G.

Author_Institution

Dept of Anesthesia & Biomed. Eng., Harvard Med. Sch., Boston, MA, USA

Volume

2

fYear

2002

fDate

2002

Firstpage

1521

Abstract

The coefficient of variation (CoV) is frequently used to describe functional or structural heterogeneity but is overestimated by the contribution of noise from the measurement method. We evaluated a method to estimate a noise-corrected heterogeneity. It delivers results with a narrow confidence interval. That method has been used to estimate the heterogeneity of pulmonary blood flow in humans as well as in animals.

Keywords

blood flow measurement; image denoising; lung; medical image processing; positron emission tomography; animals; coefficient of variation; cylindrical phantom; functional heterogeneity; humans; measurement method; narrow confidence interval; noise-corrected pulmonary blood flow heterogeneity estimation; positron emission tomography; structural heterogeneity; Anesthesia; Biomedical measurements; Blood flow; Fluid flow measurement; Humans; Imaging phantoms; Linear regression; Noise measurement; Positron emission tomography; Signal to noise ratio;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology, 2002. 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society EMBS/BMES Conference, 2002. Proceedings of the Second Joint

ISSN

1094-687X

Print_ISBN

0-7803-7612-9

Type

conf

DOI

10.1109/IEMBS.2002.1106516

Filename

1106516