• DocumentCode
    3862518
  • Title

    Efficient Acquisition and Learning of Fluorescence Microscope Data Models

  • Author

    Charles Jackson;Robert F. Murphy;Jelena Kovacevic

  • Author_Institution
    Dept. of Biomedical Eng. and Center for Bioimage Informatics, Carnegie Mellon University, Pittsburgh, PA, USA
  • Volume
    6
  • fYear
    2007
  • Abstract
    We present a method for efficient acquisition of fluorescence microscope datasets, to allow for higher spatial and temporal resolution, and with less damage from photobleaching. Our proposal is to restrict acquisition to regions where we expect to find an object. Given that the objects are continuously moving, we must have an accurate model to describe objects´ motion to predict their future locations. We outline a system for learning and applying this motion model, provide details from some simple simulations, and summarize results from more complex applications.
  • Keywords
    "Fluorescence","Microscopy","Data models","State-space methods","Photobleaching","Machine learning","Tracking","Equations","Spatial resolution","Biological system modeling"
  • Publisher
    ieee
  • Conference_Titel
    Image Processing, 2007. ICIP 2007. IEEE International Conference on
  • ISSN
    1522-4880
  • Print_ISBN
    978-1-4244-1436-9
  • Electronic_ISBN
    2381-8549
  • Type

    conf

  • DOI
    10.1109/ICIP.2007.4379567
  • Filename
    4379567