Title :
Aggregation of red cells and linear velocity gradients: influence on the correlation-based method for quantitative IVUS blood flow at 20 MHz
Author :
Lupotti, F.A. ; Zimmer, A. ; Daronat, M. ; Foster, F.S. ; van der Steen, A.F.W. ; Cloutier, G.
Author_Institution :
Thoraxcenter, Erasmus MC, Rotterdam, Netherlands
Abstract :
Recent computer simulations suggest that the presence of aggregates of red blood cells (RBCs), at random angles and lengths, does not affect the measurements of transverse blood flow using a correlation-based method and an IVUS array catheter. Blood velocity gradients were also shown not to influence the correlation-based method for blood velocity estimation. The objective of this study is to quantify the influence of aggregates of RBCs and blood velocity gradients on the correlation-based method during in vitro experiments. For this purpose, measurements were performed on normal and diseased human blood. The decorrelation pattern of a circular ultrasound transducer as a function of transverse blood flow was studied using a Couette system. Agreements were found between the auto-convolution of the acoustical beam and the RF decorrelation patterns.
Keywords :
aggregation; biomedical ultrasonics; blood flow measurement; decorrelation; ultrasonic measurement; ultrasonic transducers; velocity measurement; 20 MHz; Couette system; blood velocity gradients; circular ultrasound transducer; correlation-based method; decorrelation pattern; diseased human blood; linear velocity gradients; normal human blood; quantitative IVUS blood flow; random angles; random lengths; red cells aggregation; transverse blood flow; Aggregates; Blood flow; Catheters; Cells (biology); Computer simulation; Decorrelation; Fluid flow measurement; In vitro; Length measurement; Red blood cells;
Conference_Titel :
Ultrasonics Symposium, 2002. Proceedings. 2002 IEEE
Print_ISBN :
0-7803-7582-3
DOI :
10.1109/ULTSYM.2002.1192588
