• DocumentCode
    395242
  • Title

    Investigation of coding structure in DNA

  • Author

    Rosen, Gail L. ; Moore, Jeffrey D.

  • Author_Institution
    Center for Signal & Image Process., Georgia Inst. of Technol., GA, USA
  • Volume
    2
  • fYear
    2003
  • fDate
    6-10 April 2003
  • Abstract
    We have all heard the term "cracking the genomic code", but is DNA a code in the information theoretic sense? The coined term "genetic code" maps nucleotide triplets (codons) to amino acids. However, this is in a computer coding sense because a codon instruction is performed to output an amino acid sequence. We examine methods to detect redundant coding structures in DNA. First, a finite field framework for a nucleotide symbolic sequence is presented; then approaches to finding the sequence structure associated with error correcting codes are examined. We compare a previously proposed parity-check vector search method to a novel subspace partitioning algorithm. The subspace partitioning algorithm is a general approach to finding any linear coding redundancy. Our method provides an easy way of visualizing coding potential in DNA sequences as shown from the test data.
  • Keywords
    DNA; Galois fields; error correction codes; genetics; DNA coding structure; Galois field; amino acid sequence; codon instruction; computer coding; error correcting codes; finite field framework; genetic code; genomic code; nucleotide symbolic sequence; nucleotide triplets; parity-check vector search method; redundant coding structure; subspace partitioning algorithm; Amino acids; Bioinformatics; Computer aided instruction; DNA; Error correction codes; Galois fields; Genetics; Genomics; Partitioning algorithms; Sequences;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Acoustics, Speech, and Signal Processing, 2003. Proceedings. (ICASSP '03). 2003 IEEE International Conference on
  • ISSN
    1520-6149
  • Print_ISBN
    0-7803-7663-3
  • Type

    conf

  • DOI
    10.1109/ICASSP.2003.1202370
  • Filename
    1202370