Membrane dynamics and single-neuron signal processing

The oscillatory behaviour of both action potentials and subthreshold membrane potential, is widely accepted to be the basis of neuronal signal. An important factor of this behaviour is the frequency to which the neuron is able to oscillate. Little is known about the factors that affect this frequency or if it is modulated by some neuronal mechanism. In the present work we studied the relation between the frequency of the oscillations that display the inferior olive neural cells the passive currents, calcium-active conductances, as well as with the reversal potential of passive channels. We prove that the oscillation frequency of the inferior olive neurons can be determined by means of these parameters.