Title :
Portable array biosensors
Author :
Taitt, C.R. ; Golden, J.P. ; Shubin, Y. ; Shriver-Lake, L.C. ; Sapsford, K.E. ; Delehanty, J.B. ; Ligler, F.S.
Author_Institution :
Naval Res. Lab., Washington, DC, USA
Abstract :
The Bio-Agent Array Biosensor (BAABS) has been developed at the Naval Research Laboratory (NRL) with the goal of simultaneously detecting and identifying multiple target agents in complex samples. This paper will focus on recent improvements in both the biochemical and engineering aspects of this instrument. These new improvements have enabled the expansion of the repertoire of analytes detected, the number of replicates attainable, and the different sample matrices tested. Automation and miniaturization of the imaging and fluidics control have further brought us toward realization of a fully automated, fieldable multi-analyte biosensor.
Keywords :
arrays; biochemistry; biomedical transducers; biosensors; fluorescence; microfluidics; microsensors; portable instruments; spectrochemical analysis; Bio-Agent Array Biosensor; Naval Research Laboratory; analyte repertoire; attainable replicates; biochemical aspects; engineering aspects; fluidics control; fluorescent tracer antibody; fully automated fieldable multi-analyte biosensor; imaging automation; imaging miniaturization; multiple target agents; portable array biosensors; sample matrices; Biosensors; Electromagnetic waveguides; Fluidics; Fluorescence; Immune system; Laboratories; Optical surface waves; Optical waveguides; Proteins; Surface waves;
Conference_Titel :
Circuits and Systems, 2003. ISCAS '03. Proceedings of the 2003 International Symposium on
Print_ISBN :
0-7803-7761-3
DOI :
10.1109/ISCAS.2003.1205099
