• DocumentCode
    399933
  • Title

    Non-invasiveness, high cell viability, and high penetration of multi-harmonic generation microscopy

  • Author

    Sun, Chi-Kuang ; Chu, Shi-Wei ; Chen, Szu-Yu ; Tsai, Tsung-Han ; Liu, Tzu-Ming ; Lin, Chung-Yung ; Tsai, Huai-Jen

  • Author_Institution
    Graduate Inst. of Electro-Opt. Eng., Nat. Taiwan Univ., Taipei, Taiwan
  • Volume
    1
  • fYear
    2003
  • fDate
    27-28 Oct. 2003
  • Firstpage
    239
  • Abstract
    This paper studies live zebrafish embryos as examples in discussing penetration, cell viability, and non-invasiveness issues of harmonic generation microscopy. No optical damage can be observed during the whole proliferation process even with 100-mW incident average power on the embryo after long-term (>12 hrs) observations.
  • Keywords
    bio-optics; biological techniques; cellular biophysics; laser beam applications; optical harmonic generation; optical microscopy; 100 mW; cell viability; live zebrafish embryos; multiharmonic generation microscopy; noninvasive technique; penetration; proliferation process; Biomedical optical imaging; Embryo; Fiber nonlinear optics; Fluorescence; Laser excitation; Nonlinear optics; Optical harmonic generation; Optical microscopy; Optical scattering; Ultrafast optics;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Lasers and Electro-Optics Society, 2003. LEOS 2003. The 16th Annual Meeting of the IEEE
  • ISSN
    1092-8081
  • Print_ISBN
    0-7803-7888-1
  • Type

    conf

  • DOI
    10.1109/LEOS.2003.1251725
  • Filename
    1251725