Spike sorting in multi-channel extracellular recordings of retinas

Author

Zhang, Pu-Ming ; Wu, Jin-Yong ; Zhou, Yi ; Liang, Pei-Ji ; Yuan, Jing-Qi

Author_Institution

Dept. of Autom., Shanghai Jiao Tong Univ., China

Volume

1

fYear

2003

fDate

14-17 Dec. 2003

Firstpage

712

Abstract

Spike sorting is a prerequisite for studying the multi-channel extracellular recordings. A new method is developed for spike sorting in multi-channel extracellular recordings of retinas. Based on the assumption that noise follows Gaussian distribution, spike templates are constructed based on principal component analysis and subtractive clustering, then a template matching procedure is applied to choose the best-fit template or templates combination for overlapping spikes so that after subtracting the template or templates combination from the spike event, the sum of squared residue follows Chi-square distribution. Artificial spike trains are used to assess the performance of the proposed method.

Keywords

Gaussian distribution; eye; feature extraction; neurophysiology; principal component analysis; Chi-square distribution; Gaussian distribution; artificial spike trains; overlapping spikes; principal component analysis; retina multichannel extracellular recording; spike sorting; spike templates; subtractive clustering; template matching procedure; Electrodes; Event detection; Extracellular; Gaussian distribution; Gaussian noise; Neurons; Principal component analysis; Retina; Sampling methods; Sorting;

fLanguage

English

Publisher

ieee

Conference_Titel

Neural Networks and Signal Processing, 2003. Proceedings of the 2003 International Conference on

Conference_Location

Nanjing

Print_ISBN

0-7803-7702-8

Type

conf

DOI

10.1109/ICNNSP.2003.1279374

Filename

1279374