Title :
Multiphoton imaging of synaptic dynamics
Author :
Majewska, Ania ; Sur, Mriganka
Author_Institution :
Dept. of Brain & Cognitive Sci., Massachusetts Inst. of Technol., Cambridge, MA, USA
Abstract :
Multiphoton laser scanning microscopy is a powerful tool for studying small structures and their dynamics in living brain tissue. This paper outlines the uses of multiphoton microscopy for the in vivo imaging the structure and function of dendritic spines, which are the postsynaptic sites of synapses in the central nervous system.
Keywords :
biological tissues; biomedical optical imaging; brain; laser applications in medicine; multiphoton processes; neurophysiology; optical microscopy; central nervous system; dendritic spines; in vivo imaging; living brain tissue; multiphoton laser scanning microscopy; postsynaptic sites; synaptic dynamics; Brain; Calcium; Fluorescence; In vivo; Light scattering; Microscopy; Neurons; Optical imaging; Optical scattering; Particle scattering;
Conference_Titel :
Engineering in Medicine and Biology Society, 2003. Proceedings of the 25th Annual International Conference of the IEEE
Print_ISBN :
0-7803-7789-3
DOI :
10.1109/IEMBS.2003.1280157
