Ultrasonic separation in microfluidic capillaries

Author

Araz, Muhammet Kursad ; Lee, Chung-Hoon ; Lal, Amit

Author_Institution

Appl. & Eng. Phys., Cornell Univ., Ithaca, NY, USA

Volume

1

fYear

2003

fDate

5-8 Oct. 2003

Firstpage

1066

Abstract

We present a new actuator based on glass capillary bonded to laser-cut PZT plate, for ultrasonic control of microparticles inside microfluidic channels. The actuator generates high velocity bending modes at low CMOS compatible 5-10 Vpp drive. The high velocity enables focusing of samples at the nodes and the antinodes of the bending waves in the capillary. Separation of 3 and 10 microns polystyrene microbeads in space by 800 μm is achieved. E.Coli cells and blood cells can also be separated with particles with lower density than water being placed at the transverse velocity nodes and heavier particles at the antinodes.

Keywords

biomedical ultrasonics; blood; cellular biophysics; lead compounds; microfluidics; piezoelectric actuators; piezoelectric transducers; ultrasonic transducers; 10 micron; 3 micron; 800 micron; CMOS; E.Coli cells; actuator; bending waves; blood cells; laser cut PZT plate; microfluidic capillaries; microfluidic channels; microparticles; polystyrene microbeads; transverse velocity nodes; ultrasonic control; ultrasonic separation; velocity bending modes; water; Actuators; Bonding; Cells (biology); Energy consumption; Frequency; Glass; Impedance; Laser beam cutting; Lead; Microfluidics;

fLanguage

English

Publisher

ieee

Conference_Titel

Ultrasonics, 2003 IEEE Symposium on

Print_ISBN

0-7803-7922-5

Type

conf

DOI

10.1109/ULTSYM.2003.1293584

Filename

1293584