Title :
THz sensing of genes
Author :
Bolivar, P. Haring ; Nagel, M. ; Brucherseifer, M. ; Richter, F. ; Kurz, H. ; Bosserhoff, A. ; Buttner, R.
Author_Institution :
Inst. fur Halbeitertech., Rheinisch-Westfalische Tech. Hochschule, Aachen, Germany
Abstract :
Recent developments for the label-free analysis of genetic material using THz systems are presented. Following a proof-of-principle initial approach, high-sensitivity integrated THz sensing systems reaching femtomol detection sensitivity and single base mutation capabilities are reviewed.
Keywords :
DNA; biosensors; biotechnology; genetics; molecular biophysics; submillimetre wave devices; submillimetre waves; THz gene sensing; femtomol detection sensitivity; genetic material; integrated THz sensing systems; label-free analysis; single base mutation capabilities; Biological materials; Biomedical materials; Biomedical optical imaging; DNA; Genetic mutations; Infrared detectors; Nonlinear optics; Optical materials; Optical resonators; Ultrafast optics;
Conference_Titel :
Lasers and Electro-Optics, 2003. CLEO '03. Conference on
Conference_Location :
Baltimore, MD, USA
Print_ISBN :
1-55752-748-2
