DocumentCode
412517
Title
In-vivo targeted gene transfer to skin by nanosecond pulsed laser-induced stress waves
Author
Ogura, M. ; Obara, M.
Author_Institution
Dept. of Electron. & Electr. Eng., Keio Univ., Yokohama, Japan
fYear
2003
fDate
6-6 June 2003
Abstract
We demonstrated that laser-induced stress waves enhanced transfection efficiency in rat´s skin in vivo by a factor of 120 over the naked DNA injection. Site-and tissue specific gene expressions were observed.
Keywords
DNA; genetics; high-speed optical techniques; molecular biophysics; skin; DNA injection; enhanced transfection efficiency; in-vivo targeted gene transfer; nanosecond pulsed laser; skin; specific gene expression; stress wave; Chemical lasers; DNA; Educational institutions; Fiber lasers; Gene therapy; Laser theory; Optical fibers; Optical pulses; Skin; Stress;
fLanguage
English
Publisher
ieee
Conference_Titel
Lasers and Electro-Optics, 2003. CLEO '03. Conference on
Conference_Location
Baltimore, MD, USA
Print_ISBN
1-55752-748-2
Type
conf
Filename
1298669
Link To Document