Title :
The simulated annealing method applied to protein structure prediction
Author :
Chen, Wei-Feng ; Li, Kai-Yang ; Liu, Juan
Author_Institution :
Dept. of Phys., Wuhan Univ., China
Abstract :
In this article, a united-residue energy function containing multi-body interactions put forward by Harold A. Scheraga was described in detail. Based on the molecular modeling, the simulated annealing method was applied to the conformation space searching, and following this dynamic formation and breaking of disulfide bonds were brought forward.
Keywords :
molecular biophysics; proteins; simulated annealing; disulfide bonds; molecular modeling; protein structure prediction; simulated annealing method; united residue energy function; Biophysics; Computational modeling; Laboratories; Peptides; Potential energy; Predictive models; Proteins; Sequences; Simulated annealing; Solvents;
Conference_Titel :
Machine Learning and Cybernetics, 2004. Proceedings of 2004 International Conference on
Print_ISBN :
0-7803-8403-2
DOI :
10.1109/ICMLC.2004.1378517
