DocumentCode :
423587
Title :
In vivo evaluations of retinal prostheses
Author :
Salzmann, J. ; Linderholm, P. ; Paques, M. ; Simonutti, M. ; Chiappore, J.A. ; Safran, A.B. ; Renaud, P. ; Sahel, J. ; Picaud, S.
Author_Institution :
Eye Clinic, Geneva Univ., Switzerland
Volume :
1
fYear :
2004
fDate :
25-29 July 2004
Abstract :
In this article, the in vivo evaluation of retinal prostheses were achieved either in animals with normal vision or in blind persons. To assess the stimulating electrodes in vivo on an animal with photoreceptor degeneration, we have implanted a P23H rhodopsin rats. The present study describes the implant design and our surgical strategy. The experiments indicate clearly that the implant electrodes can be tested on a leaving rat with photoreceptor degeneration. Future studies can assess the electrode characteristics and the stimulating protocol to trigger cellular and/or animal behavior responses.
Keywords :
artificial organs; electrodes; eye; surgery; P23H rhodopsin rats; implant electrodes; in vivo evaluation; photoreceptor degeneration; retinal prostheses; stimulating electrodes; surgical strategy; Animals; Electrodes; Implants; In vivo; Photoreceptors; Prosthetics; Rats; Retina; Surgery; Testing;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Neural Networks, 2004. Proceedings. 2004 IEEE International Joint Conference on
ISSN :
1098-7576
Print_ISBN :
0-7803-8359-1
Type :
conf
DOI :
10.1109/IJCNN.2004.1379973
Filename :
1379973
Link To Document :
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