Title :
Microfabricated substrates for eukariotic cells adherence
Author :
Vasilco, R. ; Manea, E. ; Popescu, A.M. ; Ionica, E. ; Costache, M. ; Dinischiotu, A. ; Muresan, V. ; Vatasescu, R. ; Mihalcea, A.
Author_Institution :
R&D Nat. Inst. for Microtechnology, Bucharest, Romania
Abstract :
Micromachining and micro patterning of biocompatible substrates encourage the arrangement of cells in vitro following the same morphofunctional patterns as in vivo. Adherence, multiplication and differentiation in vitro of the dermal fibroblasts on surface and bulk micro fabricated substrates represent a modern method for biocompatibility testing in view of further therapeutic applications.
Keywords :
adhesion; biological tissues; cellular biophysics; micromachining; substrates; tissue engineering; biocompatible substrates; cell arrangement; dermal fibroblasts; eukariotic cells adherence; microfabricated substrates; micromachining; micropatterning; morphofunctional patterns; therapeutic applications; Cells (biology); Chemical technology; Etching; Fabrication; Glass; In vitro; In vivo; Silicon; Substrates; Surface morphology;
Conference_Titel :
Semiconductor Conference, 2004. CAS 2004 Proceedings. 2004 International
Print_ISBN :
0-7803-8499-7
DOI :
10.1109/SMICND.2004.1402862
