Title :
Sencil™ project: development of a percutaneous optical biosensor
Author :
Liao, Kuo Chih ; Richmond, F.J. ; Hogen-Esch, Thieo ; Marcu, Laura ; Loeb, Gerald E.
Author_Institution :
Alfred E. Mann Inst. for Biomedical Eng., Southern California Univ., CA, USA
Abstract :
We describe the design, fabrication method, biocompatibility test results, and first application of the novel chemical sensor technology that is under development. The sensor is designed to be minimally invasive, disposable and easily readable to make frequent measurements of various analytes in vivo over a period of 1-3 months. It uses photonic sensing of a chemical reaction that occurs in a polymer matrix bound to the internal end of a chronically implanted percutaneous optical fiber.
Keywords :
biochemistry; biomedical equipment; chemical sensors; optical fibres; polymers; skin; 1 to 3 month; Sencil; biocompatibility; chemical reaction; chemical sensor; chronically implanted percutaneous optical fiber; percutaneous optical biosensor; photonic sensing; polymer matrix; Biomedical optical imaging; Biosensors; Chemical and biological sensors; Chemical sensors; Chemical technology; Design methodology; Minimally invasive surgery; Optical device fabrication; Optical sensors; Testing; Optical fiber; Quantum dots; chemical sensor; florescence resonance energy transfer; glucose;
Conference_Titel :
Engineering in Medicine and Biology Society, 2004. IEMBS '04. 26th Annual International Conference of the IEEE
Conference_Location :
San Francisco, CA
Print_ISBN :
0-7803-8439-3
DOI :
10.1109/IEMBS.2004.1403612
