DocumentCode
429960
Title
Drug dosage level design to maximize the benefits of therapy
Author
Jeffrey, A.M. ; Xia, Xiang-Gen ; Craig, I.K.
Volume
1
fYear
2004
fDate
17-17 Sept. 2004
Firstpage
473
Abstract
Currently, antiretroviral agents are administered in a fixed dosage style. Sampling is usually done before therapy is initiated in order to decide when therapy will be initiated, then again 2-8 weeks after the initiation of therapy to assess the initial effect of therapy. The paper presents a model predictive control approach to therapy dosage scheduling when blood samples are taken at a parameter dependent fixed interval
Keywords
biocontrol; control system analysis; control system synthesis; drug delivery systems; optimisation; predictive control; scheduling; antiretroviral agents; blood samples; drug dosage level design; fixed dosage; model predictive control; parameter dependent fixed interval; therapy dosage scheduling; Blood; Drugs; Human immunodeficiency virus; Immune system; Mathematical model; Medical treatment; Optimal control; Predictive control; Predictive models; Sampling methods;
fLanguage
English
Publisher
ieee
Conference_Titel
AFRICON, 2004. 7th AFRICON Conference in Africa
Conference_Location
Gaborone
Print_ISBN
0-7803-8605-1
Type
conf
DOI
10.1109/AFRICON.2004.1406718
Filename
1406718
Link To Document