Title :
ALA-mediated photodynamic therapy decreases the ability of cellular invasion in CL1-5 human lung adenocarcinoma cells
Author :
Chen, Chin-Tin ; Chung, Kung-Yan ; Chou, Ruey-Hwang ; Chiang, Hou-Yu ; Sung-Tsang Hsieh ; Chang, Wun-Shaing
Author_Institution :
Center for Optoelectron. Biomedicine, Nat. Taiwan Univ., Taipei, Taiwan
Abstract :
In this study, we investigate the ALA-PDT induced biological responses in CL1-5 human lung adenocarcinoma cells. Under ALA-PDT, we found that mitochondrial photodamage results in phenotypic changes and reduced invasive behavior in CL1-5 cells.
Keywords :
cancer; cellular effects of radiation; laser applications in medicine; lung; organic compounds; photodynamic therapy; tumours; ALA-mediated photodynamic therapy; CL1-5 cells; adenocarcinoma cells; cellular invasion; human lung; mitochondrial photodamage; Aggregates; Aging; Cancer; DNA; Genetic mutations; Humans; Lungs; Medical treatment; Morphology; Photochemistry;
Conference_Titel :
Biophotonics, 2004. APBP 2004. The Second Asian and Pacific Rim Symposium on
Print_ISBN :
0-7803-8676-0
DOI :
10.1109/APBP.2004.1412295
