Title :
In vivo targeted gene delivery to skin by direct irradiation with nanosecond laser pulses
Author :
Ogura, M. ; Obara, M. ; Sato, S. ; Ashida, H.
Author_Institution :
Dept. of Electron. & Electr. Eng., Keio Univ., Yokohama, Japan
Abstract :
We demonstrated in vivo targeted gene delivery to rat skin by direct irradiation with nanosecond laser pulses. Expressions of enhanced green fluorescent protein (EGFP) were observed only in the area irradiated with laser pulses.
Keywords :
biochemistry; biological effects of laser radiation; genetics; patient treatment; proteins; skin; enhanced green fluorescent protein; gene delivery; in vivo target; nanosecond laser pulse irradiation; rat skin; Chemical lasers; DNA; Fluorescence; In vivo; Laser theory; Optical pulse generation; Optical pulses; Proteins; Skin; Stress;
Conference_Titel :
Biophotonics, 2004. APBP 2004. The Second Asian and Pacific Rim Symposium on
Print_ISBN :
0-7803-8676-0
DOI :
10.1109/APBP.2004.1412300
