Title :
Intravascular ultrasound tissue harmonic imaging in vivo
Author :
Frijlink, M.E. ; Goertz, D.E. ; van Damme, L.C.A. ; Krams, R. ; van der Steen, Anton F. W.
Author_Institution :
Biomed. Eng., Erasmus Univ., Rotterdam, Netherlands
Abstract :
The feasibility of tissue harmonic imaging with a prototype intravascular ultrasound (IVUS) system using a conventional single-element rotating IVUS catheter was investigated. Hydrophone measurements showed fundamental peak pressures of 1.9 MPa on-axis of such a catheter in water. The second harmonic signal at 40 MHz built up to 0.55 MPa, corresponding to 11 dB below the peak fundamental pressure. Experiments performed in a tissue-mimicking phantom and in a rabbit aorta in vivo showed the feasibility of tissue harmonic imaging with a conventional IVUS catheter. When we applied averaging of four neighboring RF-lines in the in vivo acquisition, the signal-to-noise ratio of the harmonic image increased to 25 dB.
Keywords :
biological tissues; biomedical ultrasonics; catheters; hydrophones; ultrasonic imaging; 40 MHz; hydrophone measurements; intravascular ultrasound system; rabbit aorta; single-element rotating IVUS catheter; tissue-mimicking phantom; ultrasound tissue harmonic imaging; Biomedical imaging; Catheters; Imaging phantoms; In vivo; Prototypes; Rabbits; Signal to noise ratio; Sonar equipment; Ultrasonic imaging; Ultrasonic variables measurement;
Conference_Titel :
Ultrasonics Symposium, 2004 IEEE
Print_ISBN :
0-7803-8412-1
DOI :
10.1109/ULTSYM.2004.1417976