A state space approach to noise reduction of 3D fluorescent microscopy images

Author

Ober, Raimund J. ; Lai, Xuming ; Lin, Zhiping ; Ward, E. Sally

Author_Institution

Dept. of Electr. Eng., Texas Univ., Dallas, TX, USA

Volume

2

fYear

2004

fDate

24-27 Oct. 2004

Firstpage

1153

Abstract

An algorithm is presented to calculate a state space realization of a 3D image set. It is based on interpreting the image set as the impulse response of a 3D separable system. As an application it is shown how the approximation steps, including balanced model reduction methods, in the algorithm can be used to suppress noise in 3D image sets. The approach was motivated by a practical problem in the analysis of 3D fluorescent microscopy image data of fluorescently labelled cells.

Keywords

estimation theory; image processing; interference suppression; microscopy; smoothing methods; transient response; 3D separable system; balanced model reduction method; fluorescent microscopy image data; fluorescently labelled cell; image set realization; impulse response; noise suppression; state space calculation; Biomedical imaging; Fluorescence; Immune system; Iterative algorithms; Microscopy; Noise reduction; Reduced order systems; Signal processing; Signal processing algorithms; State-space methods;

fLanguage

English

Publisher

ieee

Conference_Titel

Image Processing, 2004. ICIP '04. 2004 International Conference on

ISSN

1522-4880

Print_ISBN

0-7803-8554-3

Type

conf

DOI

10.1109/ICIP.2004.1419508

Filename

1419508