Implementation of time-of-flight on CPS HiRez PET scanner

Author

Conti, M. ; Bendriem, B. ; Casey, M. ; Chen, M. ; Kehren, F. ; Michel, C. ; Panin, V.

Author_Institution

CPS Innovations, Knoxville, TN

Volume

5

fYear

2004

fDate

16-22 Oct. 2004

Firstpage

2796

Lastpage

2800

Abstract

Time-of-flight (TOF) positron emission tomography (PET) was studied and preliminarily developed in the 80s, but the lack of a scintillator able to deliver at the same time proper time resolution and stopping power has prevented this technique from becoming widespread and commercially available. The introduction of LSO in PET has made TOF-PET a feasible option: TOF reconstruction is being implemented in CPS HiRez PET scanner, both in Filtered-Back-Projection and OSEM3D. The measured time resolution of 1.2 ns (FWHM) allows for a signal-to-noise ratio increase of about 50% in patients of about 40 cm transaxial size. TOF reconstruction has shown the expected improvement in SNR, both in simulation and experimental data. In iterative reconstruction we observed that TOF-PET has a much faster convergence compared to conventional reconstruction and better consistency improves the SNR ratio

Keywords

iterative methods; positron emission tomography; solid scintillation detectors; CPS HiRez PET scanner; Filtered-Back-Projection; LSO; OSEM3D; iterative reconstruction; scintillator; signal-to-noise ratio; stopping power; time resolution; time-of-flight positron emission tomography; Convergence; Detectors; Event detection; Image reconstruction; Positron emission tomography; Signal resolution; Signal to noise ratio; Size measurement; Technological innovation; Time measurement;

fLanguage

English

Publisher

ieee

Conference_Titel

Nuclear Science Symposium Conference Record, 2004 IEEE

Conference_Location

Rome

ISSN

1082-3654

Print_ISBN

0-7803-8700-7

Electronic_ISBN

1082-3654

Type

conf

DOI

10.1109/NSSMIC.2004.1466269

Filename

1466269