Title :
Enhancement of cell boundaries in transmission electron microscopy images
Author :
Tasdizen, Tolga ; Whitaker, Ross ; Marc, Robert ; Jones, Bryan
Author_Institution :
Inst. of Sci. Comput. & Imaging, Utah Univ., Salt Lake City, UT, USA
Abstract :
Transmission electron microscopy (TEM) is an important modality for the analysis of cellular structures in neurobiology. The computational analysis of neurons entail their segmentation and reconstruction from TEM images. This problem is complicated by the heavily textured nature of cellular TEM images and typically low signal-to-noise ratios. In this paper, we propose a new partial differential equation for enhancing the contrast and continuity of cell membranes in TEM images.
Keywords :
biomedical imaging; cellular biophysics; image reconstruction; image segmentation; image texture; partial differential equations; transmission electron microscopy; TEM; cell boundaries; cell membranes; cellular structures; contrast enhancement; images reconstruction; images segmentation; neurobiology; partial differential equation; signal-to-noise ratios; transmission electron microscopy images; Biomembranes; Cells (biology); Cities and towns; Image analysis; Image reconstruction; Image segmentation; Magnetic resonance imaging; Neurons; Noise reduction; Transmission electron microscopy;
Conference_Titel :
Image Processing, 2005. ICIP 2005. IEEE International Conference on
Print_ISBN :
0-7803-9134-9
DOI :
10.1109/ICIP.2005.1530008
