DocumentCode
445445
Title
Investigation in vivo the effect of temperature on quantum yield of photodissociation of oxyhemoglobin (HbO2) in cutaneous blood vessels
Author
Asimov, M.M. ; Asimov, R.M. ; Mamilov, S.A. ; Plaksiy, Yu.S. ; Rubinov, A.N. ; Gisbrecht, A.I.
Author_Institution
Inst. of Phys., Nat. Acad. of Sci. of Belarus, Minsk, Belarus
Volume
1
fYear
2005
fDate
12-17 Sept. 2005
Firstpage
279
Abstract
The temperature effect on laser-induced photodissociation of oxyhemoglobin in vivo by measuring changes in arterial blood oxygen saturation is investigated. It is shown that during laser irradiation the local concentration of free oxygen in tissue significantly increases when temperature of the body exceeds 40°C compare to normal one. Different biomedical applications of this phenomenon are proposed. Unique possibility in selective and local increase of the concentration of free molecular oxygen in tissue that enhances metabolism of cells is demonstrated. An important conclusion is drawn from the obtained results that temperature dependence of quantum yield of photodissociation of oxyhemoglobin should be taken into account in developing new therapeutic methods for laser medicine.
Keywords
biological effects of laser radiation; biothermics; blood vessels; cellular effects of radiation; laser applications in medicine; oxygen; photodissociation; O2; arterial blood oxygen saturation; biomedical application; body temperature effect; cell metabolism; cutaneous blood vessels; free molecular oxygen concentration; laser irradiation; laser medicine; laser-induced photodissociation; oxyhemoglobin; photodissociation; tissue; Blood vessels; Cancer; Fingers; In vivo; Laser modes; Medical treatment; Pulse measurements; Signal processing; Temperature dependence; Testing;
fLanguage
English
Publisher
ieee
Conference_Titel
Advanced Optoelectronics and Lasers, 2005. Proceedings of CAOL 2005. Second International Conference on
Print_ISBN
0-7803-9130-6
Type
conf
DOI
10.1109/CAOL.2005.1553882
Filename
1553882
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