Title :
Studies toward the enantioselective total synthesis of 3/spl alpha/-hydroxy-15-rippertene
Author :
Kreuzer, Thomas ; Metz, Peter
Author_Institution :
Dresden Univ. of Technol.
fDate :
June 26 2004-July 3 2004
Abstract :
The tetracyclic diterpene 3alpha-hydroxy-15-rippertene (1) was isolated from the defensive secretion of the higher termites Nasutitermes rippertii and Nasutitermes ephratae by Prestwich et al. Herein we report the synthesis of two advanced hydroazulene key intermediates for the enantioselective total synthesis of 1
Keywords :
catalysis; chemical exchanges; isomerisation; materials preparation; organic compounds; oxidation; 3alpha-hydroxy-15-rippertene; Lewis acid-catalyzed ring expansion; Nasutitermes ephratae; Nasutitermes rippertii; copper induced allylic substitution; defensive secretion; enantiomeric isolation; enantioselective total synthesis; hydroazulene key intermediates; oxidation; termites; tetracyclic diterpene; Chemical technology; Chemistry; Civil engineering; Copper; Fluids and secretions; Isolation technology; Oxidation; Platinum; Silicon; Skeleton;
Conference_Titel :
Science and Technology, 2004. KORUS 2004. Proceedings. The 8th Russian-Korean International Symposium on
Conference_Location :
Tomsk
Print_ISBN :
0-7803-8383-4
DOI :
10.1109/KORUS.2004.1555536
