The molecules module of the brain architecture management system

We describe in this paper a new module of the brain architecture management system (BAMS; http://brancusi.usc.edu/bkms). The molecules module of BAMS makes this the first online knowledge management system that handles chemoarchitectonical data of brain regions in multiple species. This module allows insertion of complex reports of molecule presence as collated from the literature. The database structure of the module includes representation of molecule expression in different cell types as revealed by various techniques, coexpression data in different brain regions or cell types, and the physiological state of experimental animals. The module also allows insertion of time dependent experimental data. The Web interface of this module allows users to construct lists of brain regions where a molecule is present depending on the physiological state, retrieve further details about inserted records, and compare the time dependent data within or across experiments.