Differentiation of optical active form and racemic form of amphetamine-type stimulants by terahertz spectroscopy

Author

Kishi, T. ; Kanamori, T. ; Tsujikawa, K. ; Iwata, Y.T. ; Inoue, H. ; Ohtsuru, O. ; Hoshina, H. ; Otani, C. ; Kawase, K.

Author_Institution

National Res. Inst. of Police Sci., Chiba, Japan

Volume

1

fYear

2005

fDate

19-23 Sept. 2005

Firstpage

184

Abstract

Abuse of amphetamine-type stimulant (ATS) is increased in Japan. Most ATS has optical isomers and their stimulatory effects are different between optical active forms and racemic form. We applied terahertz spectroscopy to differentiate the optical active form and racemic form in solid phase. Most of spectra of two different forms showed different spectral pattern and terahertz spectroscopy can be useful for differentiation of optical isomers from racemic form.

Keywords

chemical analysis; drugs; organic compounds; submillimetre wave spectra; submillimetre wave spectroscopy; amphetamine-type stimulants; optical active form; optical isomers; racemic form; solid phase; spectral pattern; stimulatory effects; terahertz spectroscopy; Biomedical optical imaging; Central nervous system; Drugs; Infrared detectors; Laboratories; Optical interferometry; Optical mixing; Solids; Spectroscopy; Stimulated emission;

fLanguage

English

Publisher

ieee

Conference_Titel

Infrared and Millimeter Waves and 13th International Conference on Terahertz Electronics, 2005. IRMMW-THz 2005. The Joint 30th International Conference on

Print_ISBN

0-7803-9348-1

Type

conf

DOI

10.1109/ICIMW.2005.1572469

Filename

1572469