Title :
Raman-tweezers sensing: fast detection and discrimination of bacterial spores and vegetative cells
Author :
Xie, Changan ; Mace, Jason ; Dinno, Mumtaz A. ; Li, Yong-qing ; Tang, Wei ; Newton, Ronald J.
Author_Institution :
Dept. of Phys., East Carolina Univ., Greenville, NC, USA
Abstract :
Raman-tweezers spectroscopy has been used for the rapid detection of dipicolinic acid (DPA) of single bacterial spores and reagentless discrimination of different species of bacterial cells with principal component analysis and cluster analysis.
Keywords :
Raman spectroscopy; biohazards; biological techniques; cellular biophysics; microorganisms; molecular biophysics; optical sensors; organic compounds; principal component analysis; radiation pressure; DPA; Raman-tweezers sensing; Raman-tweezers spectroscopy; bacterial cell; cluster analysis; dipicolinic acid detection; principal component analysis; reagentless discrimination; single bacterial spore; vegetative cell; Biomedical optical imaging; Biosensors; Cells (biology); Fungi; High speed optical techniques; Microorganisms; Optical sensors; Principal component analysis; Raman scattering; Spectroscopy;
Conference_Titel :
Lasers and Electro-Optics, 2005. (CLEO). Conference on
Print_ISBN :
1-55752-795-4
DOI :
10.1109/CLEO.2005.201973
