High resolution PET imaging characteristics of /sup 68/Ga, /sup 124/I and /sup 89/Zr compared to /sup 18/F

Author

De Jong, Hugo W A M ; Perk, Lars ; Visser, Gerard W M ; Boellaard, Ronald ; Van Dongen, Guus A M S ; Lammertsma, Adriaan A.

Author_Institution

Dept. of Nucl. Medicine, VU Univ. Medical Center, Amsterdam

Volume

3

fYear

2005

fDate

23-29 Oct. 2005

Firstpage

1624

Lastpage

1627

Abstract

In this study the imaging characteristics influencing the quantitative accuracy of ⁶⁸Ga, ¹²⁴I and ⁸⁹Zr were determined and compared to those of ¹⁸F using a 3D high resolution PET (high resolution research tomograph, HRRT) scanner. Although there were large discrepancies found in the sensitivity of these isotopes, which can be explained by their positron abundancy, none of the assessed imaging characteristic prevents the isotopes for usage in (high resolution) quantitative PET imaging. Care has to be taken, however, that accurate correction methods are used for dead time, background and scatter, and partial volume

Keywords

image resolution; medical image processing; positron emission tomography; HRRT; background; correction methods; dead time; high resolution PET imaging characteristics; high resolution research tomograph; isotope sensitivity; partial volume; scatter; Biomedical imaging; High-resolution imaging; Image reconstruction; Image resolution; Imaging phantoms; Isotopes; Linearity; Positron emission tomography; Scattering; Zirconium;

fLanguage

English

Publisher

ieee

Conference_Titel

Nuclear Science Symposium Conference Record, 2005 IEEE

Conference_Location

Fajardo

ISSN

1095-7863

Print_ISBN

0-7803-9221-3

Type

conf

DOI

10.1109/NSSMIC.2005.1596630

Filename

1596630