Title :
High resolution PET imaging characteristics of /sup 68/Ga, /sup 124/I and /sup 89/Zr compared to /sup 18/F
Author :
De Jong, Hugo W A M ; Perk, Lars ; Visser, Gerard W M ; Boellaard, Ronald ; Van Dongen, Guus A M S ; Lammertsma, Adriaan A.
Author_Institution :
Dept. of Nucl. Medicine, VU Univ. Medical Center, Amsterdam
Abstract :
In this study the imaging characteristics influencing the quantitative accuracy of 68Ga, 124I and 89 Zr were determined and compared to those of 18F using a 3D high resolution PET (high resolution research tomograph, HRRT) scanner. Although there were large discrepancies found in the sensitivity of these isotopes, which can be explained by their positron abundancy, none of the assessed imaging characteristic prevents the isotopes for usage in (high resolution) quantitative PET imaging. Care has to be taken, however, that accurate correction methods are used for dead time, background and scatter, and partial volume
Keywords :
image resolution; medical image processing; positron emission tomography; HRRT; background; correction methods; dead time; high resolution PET imaging characteristics; high resolution research tomograph; isotope sensitivity; partial volume; scatter; Biomedical imaging; High-resolution imaging; Image reconstruction; Image resolution; Imaging phantoms; Isotopes; Linearity; Positron emission tomography; Scattering; Zirconium;
Conference_Titel :
Nuclear Science Symposium Conference Record, 2005 IEEE
Conference_Location :
Fajardo
Print_ISBN :
0-7803-9221-3
DOI :
10.1109/NSSMIC.2005.1596630
