Title :
Genomic Signals for the Study of Multiresistance Mutations in M Tuberculosis
Author :
Cristea, Paul ; Tuduce, Rodica ; Banica, Dorina ; Rodewald, Karin
Author_Institution :
Univ. "Politehnica" of Bucharest, Bucharest
Abstract :
The genomic signal analysis of nucleotide sequences reveals features difficult to identify using only the symbolic representation in the genomic data bases. Some genomic signal features correlate well with functional features at phenotype level. The paper presents results of GSA applied in the study of Mycobacterium tuberculosis rpoB gene mutations known to confer rifampin resistance.
Keywords :
database management systems; diseases; feature extraction; genetics; medical signal processing; sequences; Mycobacterium tuberculosis rpoB gene mutation; feature identification; genomic data base; genomic signal analysis; nucleotide sequence; rifampin resistance; symbolic representation; Biochemistry; Bioinformatics; Diseases; Drugs; Genetic mutations; Genomics; Immune system; Pathogens; Sequences; Signal analysis;
Conference_Titel :
Signals, Circuits and Systems, 2007. ISSCS 2007. International Symposium on
Conference_Location :
Iasi
Print_ISBN :
1-4244-0969-1
Electronic_ISBN :
1-4244-0969-1
DOI :
10.1109/ISSCS.2007.4292708
